Endometrial Receptivity Analysis (ERA)
Endometrial Receptivity Analysis (ERA)
What is Endometrial Receptivity?
Endometrial Receptivity Analysis focuses on the ability of the uterine lining to perform the implantation during IVF. It also shows the sufficiency of thickness for the development and nourishment of the embryo (egg). Endometrial Receptivity takes place if the earlier embryo transfer fails, unsuccessful pregnancy or other reasons of infertility. Endometrial Receptivity Analysis is a test to analyse the thickness of the uterine lining and ability to check endometrium for the implantation of the embryo at the right time when the window is completely ready for the implantation. The analysis helps to detect endometrium for embryo implant, which takes place between 6 to10 days after ovulation. ERA determination enhances the chance of successful pregnancy and ideal timing, as its persistence for progesterone administration before the transfer of the embryo helps for a better result. Hence, successful pregnancy can only take place if the window is responsive.
Understanding Endometrium:
Endometrium plays an important role in conceiving pregnancy, as it is one of the most important parts of the female reproductive system. The endometrium is the lining tissue present in the uterus. The hormones are helpful in thickening the endometrial layer of the uterine, which is essential in the preparation of the uterus for embryo transplant. Endometrium has three phases divided into days, such as:
- The thickening and growth phase is known as the proliferative phase that starts from days 1 to 14.
- Preparing for the implantation phase, known as the secretory phase, starts from days 15 to 28.
- Release and regeneration, commonly known as the menstrual phase, during days 1 to 5.
Estrogen and progesterone manage the growth of endometrium. It helps in the preparation of thickening the layer of the uterus so it can face a successful embryo implantation.
Reasons and conditions for pregnancy failure:
- Failure in the openness of the window.
- The embryos are insufficient to be implanted.
- Chromosomal abnormalities of the embryos.
- Failure of endometrium, as it is unsuccessful in activiness and the expressing of appropriate genes or is not in an accepting condition.
The window of receptivity is appropriate in both, whether you are conceiving it naturally or through In-Vitro Fertilization. It is different for every one, as the hormone level and progesterone level are different in the body and everyone has different endometrium expression of genes.
How does the Endometrial Receptivity Analysis (ERA) take place?
There are several procedures a woman has to go through before a successful pregnancy, endometrial receptivity analysis is one of those. Endometrial Receptivity Analysis is basically a molecular test that examines the receptivity of endometrium for implantation of embryos. Let’s be more clear about how the procedure takes place:
- Oral medications and self-injected medicines are prescribed for the stimulation and growth of the uterine lining. An ultrasound and blood test are monitored to see the tranvaginal changes.
- Endometrial biopsy of the uterine lining is examined by doctors.
- RNA extraction is a sample of gene profile to analyze the gene panel.
- As a result of the biopsy, the doctors will analyze whether the endometrium is responsive or not for the implantation of the embryo.
- As a result of non-receptivity, the doctors will reschedule or delay the embryo implantation. And increase the doses of progesterone for better stimulation.
Endometrial Receptivity Analysis in India
India is the most prominent country for medical treatment. It is also considered a medical hub. India provides the best facilities with advanced machines and technology. Endometrial Receptivity Analysis in India is much more cost effective compared to western countries. Treatment in India provides you with a skilled and experienced team of doctors and nursing staff with the utmost personalized plan for foreign patients.
Choosing the best fertility clinics
Choosing the best hospital in India can be difficult, as it provides you with a large list of hospitals. To make it easier, here are some well known hospitals you can opt for. Some of the best Endometrial Receptivity centres in India can assure personalised treatment plans and dedicated coordinators for patients.
Some of the best fertility clinics are listed below:
- World IVF Centre
- Baby Science
- Birla Fertility
- ART Clinics
- SCI IVF Hospital.
- Ferticity Fertility Clinic
Lets conclude
Endometrial Receptivity Analysis is a test to analyse the thickness of the uterine lining and ability to check endometrium for the implantation of the embryo at the right time when the window is completely ready for the implantation. Endometrial Receptivity Analysis focuses on the ability of the uterine lining to perform the implantation during IVF. It also shows the sufficiency of thickness for the development and nourishment of the embryo (egg).
FAQs
What is Endometrial Receptivity Analysis?
Answer. Endometrial Receptivity Analysis is a test to analyse the thickness of the uterine lining and ability to check endometrium for the implantation of the embryo at the right time when the window is completely ready for the implantation.
What is Endometrium?
Answer. The endometrium is the lining tissue present in the uterus. The hormones are helpful in thickening the endometrial layer of the uterine, which is essential in the preparation of the uterus for embryo transplant.
Which cities are best for Endometrial Receptivity treatment in India?
Answer. Delhi, Mumbai, Chennai and Bangalore can be considered as the best options in terms of medical.
Is India a good option for Endometrial Receptivity?
Answer. Yes, no doubt India is a good option for any fertility treatment.
