DNA Fragmentation Index of Sperm (DFI): An Introduction

Infertility among couples is a very common problem in today’s era. Reasons can be many, some known and some might be unknown. DNA Fragmentation Index of Sperm is used to measure the damage caused to DNA, the sperm genetic material. It is a technique to identify the quality of the sperm and to detect the destruction of sperm. Infertility can be caused by the poor quality of sperm and damage to sperm DNA.

According to the DNA Fragmentation Index, less than 15% fragmentation is considered an excellent quality of sperm. 15-25 % DFI can be said to be good or fair enough to produce a better quality of sperm. 25-50 % fragmentation comes between good and poor quality of sperm. After that, more than 50% DFI is clearly proved to be the very poor quality of sperm in the DFI fragmentation index. The fertility range of male sperm quality lies between 0-31%. More than this, the chance of infertility increases.

DFI is clearly used to check the integrity of the sperms that are present in the sperm head and can measure the fertile range.

The Importance of Assessing DNA Fragmentation Index (DFI) in Male Fertility

DNA Fragmentation Index (DFI) is important to check the chromosomes of the sperm that lead to the result of pregnancy. Chromosomes are made by the formation of sperm, it becomes inadequate when a DNA strand splits and it results in DNA reproduction. The sperm DNA or the DNA fragmentation affects the sperm quality. The parameters that we measure in the routine semen analysis has nothing to do with Sperm DNA fragmentation. The DNA fragmentation technology helps to use the best quality sperm for fertilization. Sometimes the reason for infertility is unknown but after introducing the DFI the reason can be explained more clearly.

According to the experts, infertility can be defined as unprotected sexual intercourse for a year and still faces failure in pregnancy. Approximately 50% of cases of infertility are because of male factors, 20% are completely due to male factors, and 30% are because of both male and female factors.

Risk Factors of DNA Fragmentation Index of Sperm

We will discuss here the factors that may be the reason for poor sperm quality and lead to the reason for infertility. Some reasons are listed below:

Genetic disorders.
Infertility family history.
Smoking and consumption of alcohol.
Obesity or stress.
Treatment of cancer (chemotherapy and radiation).
Any past surgery or trauma.
Hormonal imbalances like hypogonadism.
Infections like orchitis and epididymitis.
Exposure to electromagnetic radiation.
Poor diet and low intake of antioxidants.

These factors can be recovered due to changes in lifestyle and diet.

DNA Fragmentation Index of Sperm (DFI) in India

India is a well-known country for medical treatments. Treatment of infertility is available in India at a reasonable cost. Specialists in infertility treatment provide you with personalized plans according to your needs. All the facilities with high-tech, advanced machines are available at budget-friendly costs. Checking the DNA Fragmentation Index (DFI) in India can be more cost effective compared to western countries. Considering any IVF treatment in India will be beneficial in terms of cost, facilities and expert doctors. India’s healthcare sector is where compassion meets excellence. From routine check-ups to complex surgeries, it serves as a one-stop destination with top-notch facilities.

DNA Fragmentation Index of Sperm Treatment Centre in India

Some of the best DNA Fragmentation Index of Sperm Centres in India can assure personalised treatment plans and dedicated coordinators for patients. Prices may vary on the choice of centre.

Some of the well known DNA Fragmentation Index of Sperm centres in India are as follows:

World IVF Centre
Baby Science
Birla Fertility
ART Clinics
SCI IVF Hospital.
Ferticity Fertility Clinic

Conclusion

DNA Fragmentation Index of Sperm is used to measure the damage caused to DNA, the sperm genetic material. It is a technique to identify the quality of the sperm and to detect the destruction of sperm. DFI is clearly used to check the integrity of the sperms that are present in the sperm head and can measure the fertile range. DFI is important to check the chromosomes of the sperm that lead to the result of pregnancy.