Preimplantation Genetic Screening (PGS) – Preimplantation Genetic Diagnosis (PGD)

Testing of genetic splits into two parts: Preimplantation genetic screening (PGS) and Preimplantation genetic diagnosis (PGD).

Let’s make it easier to understand.

According to the testing techniques of PGS and PGD, it analyzes the biopsied cells from the screen so it can detect any genetic abnormalities or genetic disorders when there are no clear symptoms.

The very first point that comes to mind is genetic screening. Screening is a term referred to as monitoring or analyzing. Genetic screening is the prior monitoring of a disease or any abnormalities that are born through DNA. It includes testing of an individual’s mutations or any genetic disorder. Inherited disorder can be identified, predisposition can be identified and screening also guides in reproductive decisions.

Secondly, let’s know about genetic diagnosis.

Diagnosis is a term used to find out the reason for the disease when it is present and why it is occurring.

Also be informed about what preimplantation is? If you are considering IVF in the future, you should know about preimplantation.

Preimplantation is the first stage of the uterus where fertilized eggs (embryos) are implanted. The procedure takes place through assisted reproductive technique.

What is the need of PGS and PGD in IVF?

According to preimplantation genetic screening, it can be proved beneficial in analyizing the biopsied cells from the screen so it can detect any genetic abnormalities, genetic disorders when there are no clear symptoms.

Similarly, Preimplantation genetic diagnosis applies the same method to discover the exact and specific disorder that may pass from parents to their offspring. In vitro fertilization is a medical procedure to conceive a pregnancy, but it has to go through many procedures before getting conceived. Doctors need to be sure that if anyhow, no chromosomal should be passed on. No genetic abnormality should be transferred.

Advantages of PGD and PGS

1) Success rates are high in PGS as it helps in selecting the perfect embryos with the correct number of chromosomes for implantation that help to diminish the need for ivf.

It helps in reducing the risk of miscarriage by selecting the normal embryos with the right number of chromosomes. As generally miscarriage happen because of abnormal chromosomes

Ray of hope for older couples and especially women, as with age, the abnormalities of chromosomes increase in women. PGS helps in diagnosis and identifies the healthy embryos for implantation who go through ivf.

Reducing the chance of multiple pregnancies as PGS helps in identifying high quality embryos, which can be implanted. Lowering the possibility of multiple pregnancies that carry higher risk for both mother and baby.

It helps in the detection of chromosomal disorders. It can screen abnormalities like Down syndrome or Turner syndrome before implantation or any potential risk.

Drawbacks of PGD and PGS

Benefits and drawbacks are the part of every treatment, Preimplantation genetic screening (PGS) and Preimplantation genetic diagnosis (PGD) have their own. Here are some of them:

Expensive

PGS is an incredible process for people with complicated pregnancies but it is very expensive when it comes to cost and later on adding the overall cost of ivf.

Embryo loss risk

The PGS follows biopsy in order to diagnose the possible threat in embryos. It can sometimes damage or affect the embryos or the development potential of embryos. The removal of a sample of cells and a piece of tissues is performed under biopsy (in PGS cases).

Inaccurate result

Although in rare cases, the testing may produce inaccurate results or false results during the selection of normal embryos or the discarding of healthy embryos.

No guarantee of success

No doubt PGS aids in diagnosing high quality embryos for the selection of implantation. Despite that, it doesn’t guarantee a successful pregnancy. As factors beyond chromosomes do affect the embryos as well like the quality of embryos and uterine environment which can still affect the outcome.

PGS and PGD in India

PGS and PGD are a new invention to medical science, as it helps the doctors monitor the embryos before they get implanted in the uterus. It can analyze the embryo before implanting it and also it enhances the chance of a healthy foetus. PGD and PGS in India can be proved as a better option as it has advanced machines. An excellent team of doctors that will lead you in the whole process. Most effectively, it is cost effective. All the screening and diagnosis of implantation will be at affordable rates. Although it is not available in every fertility clinic because it is considered to be one of the most expensive in IVF treatment. Comparatively it is far better than western countries in terms of affordable rates.

PGS and PGD centres in India

India furnishes you with a vast range of hospitals and clinics. India provides you the facility of all treatments related to IVF with unconditional affection and care just to fulfil your desire of parenthood.

Some of the well known PGS and PGD centres in India are as follows:

World IVF Centre
Baby Science
Birla Fertility
ART Clinics
SCI IVF Hospital.
Ferticity Fertility Clinic

FAQs

Let’s get started with quick questions that will provide the necessary details

Which city is the best Preimplantation genetic screening (PGS) and Preimplantation genetic diagnosis (PGD) for in India?

Answer. Delhi, Mumbai, Bangalore and Chennai can be the better option for such treatment.

Who can opt for PGD and PDS?

Answer. Anyone who is considering IVF treatment for their pregnancy can opt for PGD and PGS.

Is PGD and PGS available in India?

Answer. Yes, PGD and PGS available in India

Conclusion

PGS analyzes the biopsied cells from the screen so it can detect any genetic abnormalities, genetic disorders when there are no clear symptoms. PGD technique is used to discover the exact and specific disorder which may pass from parents to their offsprings. Reducing the chance of multiple pregnancy as PGS helps in identifying high quality embryos, which can be implanted.

Preimplantation Genetic Screening (PGS)

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Dr. Ila Gupta

Dr. Abha Majumdar

Dr. Rita Bakshi

Dr. Prerna Gupta

Dr Nalini Mahajantor

Dr. Ila Gupta

Dr. Abha Majumdar

Dr. Rita Bakshi